Fig. 5

Cell administration modulates the recruitment of immune cells into the ischemic tissues. A Representative images of macrophages (MOMA-2, red) and B) neutrophils (Ly-6G, red) detected on day 21 by IHC in the limb muscles of all groups (BR: SH, IC, AT, CB, n:8 per group; technical replicates: n:3/group). Graphical representations of the number of C) macrophages and D) neutrophils quantified (cells/cm2) in IHC sections of all groups (BR: SH, IC, AT, CB, n:8 per group; technical replicates: n:3/group). Data are presented as the mean ± SEM, and statistically significant differences are shown after performing Kruskal–Wallis and Dunn’s test as post-hoc (* p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001)