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Table 1 Cox regression analysis of risk factors for cancer-related death in ESCC patients

From: Decreased plasma gelsolin fosters a fibrotic tumor microenvironment and promotes chemoradiotherapy resistance in esophageal squamous cell carcinoma

Characteristics

Univariate analysis

Multivariate analysis

HRa (95% CIa)

p valueb

HRa (95% CIa)

p valueb

pGSN expression level

High

1

0.007

1

0.059

Low

1.877 (1.190–2.961)

1.626 (0.982–2.694)

Age

 ≥ 55

1

0.283

1

0.890

 < 55

0.988 (0.967–1.010)

0.969 (0.619–1.517)

Gender

Female

1

0.237

1

0.317

Male

1.842 (0.670–5.069)

1.799 (0.570–5.681)

Alcohol

No

1

0.569

1

0.712

Yes

1.223 (0.612–2.444)

0.848 (0.355–2.029)

Smoker

No

1

0.277

1

0.202

Yes

1.446 (0.744–2.809)

1.547 (0.792–3.022)

Stage

I, II, III

1

0.021

1

0.172

IV

1.715 (1.086–2.710)

1.432 (0.856–2.398)

  1. aHR: Hazard ratio; CI: Confidence interval
  2. bBold values indicate statistical significance (p < 0.05)