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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: The endoplasmic reticulum degradation-enhancing α-mannosidase-like protein 3 attenuates the unfolded protein response and has pro-survival and pro-viral roles in hepatoma cells and hepatocellular carcinoma patients

Fig. 6

EDEM3 is correlated with treatment response in HCC patients. A Kaplan Meier curve shows overall survival of HCC patients from the TCGA database (n = 364), in relation to EDEM3 expression. B Multivariate Cox proportional hazard analysis was conducted to evaluate the hazard ratio of EDEM3 for overall survival among clinicopathological features in the TCGA-LIHC cohort. The analysis was performed by using the gtsummary 1.7.2, survival 3.5.8 and survminer 0.4.9 packages. EDEM3 expression in response to Sorafenib treatment in HepG2 cells (C), Huh7 cells (D) and HCC patients (E). The public databases used are shown in corresponding figures. The data were analyzed by using the unpaired t-test (*p < 0.05, **p < 0.01, ****p < 0.0001)

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Journal of Biomedical Science

ISSN: 1423-0127