Fig. 8
From: miR-200c inhibition and catalase accelerate diabetic wound healing
Anti-miR-200c and CAT treatment decrease DFU FBs and KCs cytotoxicity and their action is synergic. a, b FBs and KCs of HS were infected either with a lentivirus encoding miR-200c or with a control virus. After 16 h cytotoxicity assay was performed. miR-200c overexpression increased cytotoxicity (N = 6; *P < 0.05). c, d FBs and KCs of DFU pts were infected either with a lentivirus encoding anti-miR-200c or with a control virus (anti-miR-scr). Afterwards, cells were incubated with 400 UI/ml CAT for additional 16 h. Cytotoxicity assay was performed (N = 6; *p < 0.05; **p < 0.01; ***p < 0.001)