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From: Multifunctional hyaluronic acid-based biomimetic/pH-responsive hybrid nanostructured lipid carriers for treating bacterial sepsis
Test ligand
Kd (µM)
TLR2
TLR4
PGN
23.945 ± 0.880
–
LPS
38.145 ± 1.440
HA
0.8237 ± 0.414
0.045 ± 0.750
Lys
2.785 ± 0.740
43.530 ± 2.352
HA-Lys
0.0207 ± 0.848
0.187 ± 0.733
VCM-HNLCs
4.551 ± 0.485
2.443 ± 2.168
Non-hybrid NLCs components
202.1 ± 1.360
52.289 ± 2.206