Table 3 Kinetics of drug release data for the VCN-HNLCs at pH 7.4 and pH 6

Zero Order

Q = k·t

− 0.1692

− 0.4824

24.2663

37.0378

First Order

Q = Q0·e^kt

0.7468

0.9757

11.2864

4.5383

Higuchi

Q = k·t^1/2

0.7936

0.7399

10.1912

15.4195

Korsmeyer-Peppas

Q = k·tⁿ

0.8825

0.9103

8.0393

9.9941

0.360

0.324

Hixson-Crowell

Q^1/3 = kt + Q₀^1/3

0.6497

0.8000

13.2770

13.3885

Weibull

Q = 1 exp [-(t)a/b]

0.9507

0.9914

5.4391

3.1356

0.472