Journal of Biomedical Science

Table 5 ΣFIC values against S. aureus and MRSA at pH 7.4 and pH 6.0

From: Multifunctional hyaluronic acid-based biomimetic/pH-responsive hybrid nanostructured lipid carriers for treating bacterial sepsis

FIC against S. aureus
Time (h)	24	48	72	24	48	72
Time (h)	pH 7.4			pH 6
FIC (Bare VCM)	0.500	0.500	0.250	0.251	0.126	0.126
FIC (Blank HNLCs)	0.121	0.121	0.121	0.061	0.061	0.061
ΣFIC	0.621	0.621	0.371	0.312	0.187	0.187
Interpretation	Additive	Additive	Synergy	Synergy	Synergy	Synergy

FIC against MRSA
Time (h)	24	48	72	24	48	72
Time (h)	pH 7.4			pH 6
FIC (Bare VCM)	0.500	0.500	0.250	0.250	0.125	0.125
FIC (Blank HNLCs)	0.121	0.212	0.121	0.061	0.061	0.061
ΣFIC	0.621	0.621	0.621	0.311	0.186	0.186
Interpretation	Additive	Additive	Additive	Synergy	Synergy	Synergy

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ISSN: 1423-0127

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