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Table 2 ROS generation and Dectin-1 expression in PMNs from HS and TB patients

From: Variants of human DECTIN-1 rs16910526 are linked to differential reactive oxygen species production and susceptibility to tuberculosis

 

HS

TB

P value HS vs TB

ROS (MFI)

712,7 ± 26,03

512,1 ± 25,43

0.0001a

ROS (index)

3,8 ± 0,23

2,7 ± 0,26

0.0001a

Dectin-1 (MFI)

22,3 ± 1,4

14,5 ± 1,1

0.051

  1. ROS (MFI), Mean Fluorescence Intensity of Oxidized DHR emission by flow cytometry in the FL-1 channel. ROS index, ROS generated in the presence of Mtb compared to that of the controls. Dectin-1 (MFI), Mean Fluorescence Intensity of Dectin-1 expression in fresh peripheral blood PMNs assessed by labelling with anti-Dectin-1-PE antibodies using flow cytometryThe values are expressed as the mean ± standard deviation (SEM).
  2. aP values were calculated using the Mann–Whitney U test for unpaired and nonparametric samples
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Journal of Biomedical Science

ISSN: 1423-0127