Journal of Biomedical Science

Table 3 Distribution of genotypes and allele frequencies of the rs16910526 SNP variant among patients (TB) and healthy subjects (HS)

From: Variants of human DECTIN-1 rs16910526 are linked to differential reactive oxygen species production and susceptibility to tuberculosis

	TB # (%)	HS # (%)	p value TB vs HS	OR (95% CI)/p value
Genotypes^aN = 178
AC	18 (23)	10 (12)	0.037^b	2.55 (1.1–5,9)/ < 0,03^b
AA	62 (77)	88 (89.8)	0.037^b	2.55 (1.1–5,9)/ < 0,03^b
Alleles N = 356
C	18 (11.2)	10 (5.1)	0.046^b	2.36 (1.06–5.26)/ < 0,04^b
A	142 (88.8)	186 (94.9)	0.046^b	2.36 (1.06–5.26)/ < 0,04^b

^aDominant model AC vs AA. ^bP values were calculated by Fisher’s exact test. OR, odds ratio risk analysis. The genotypes were in Hardy‒Weinberg equilibrium (Ho = 0; observed – expected by HW): chi-square (χ2) test ns (p = 0.77473)

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ISSN: 1423-0127

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